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The explosion in Information and Communication Technology (ICT) has offered several opportunities to both teachers and learners to teach and learn chemistry objectively through e-learning. This paper addresses enhancement of teaching and learning of chemistry through asynchronous e-learning. The paper employs secondary sources of data from reports, journal, and findings of other researchers. Overview of the concept of asynchronous learning, benefits of asynchronous learning as flexible, self-paced, sufficient time to reflect and process course information, gives room for collaboration, solves the problem of the voluminous syllabus, solves the problem of hazardous practical, and motivates introvert students. The paper also outlines some constraints of asynchronous learning as; technophobia, poor funding, Poor Power Supply in the Country, poor maintenance and insecurity. The study recommends that efforts should be made by the government to expose science teachers to pre-service, in-service training in form of seminars and workshops, adequate funding to procure ICT gadgets, regular power supply, good maintenance culture and security of the ICT gadgets.
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